Macular Degeneration Treatment Breakthrough

A macular degeneration treatment breakthrough is making headway using a wireless retinal implant.

Pixium, a Paris based company has developed a system that may enhance vision by stimulating degenerated photoreceptor cells in patients with advanced dry macular degeneration. The system called Photovoltaic Retinal Implant (PRIMA) consists of 4 components.



1.  A pair of glasses that include a miniature camera and a data transmitter

2.  A miniature wireless subretinal chip

3.  A pocket size digital signal processor that transforms light into electric signals

4. Software that can be individualized for each patient

macular degeneration treatment breakthrough

Feasibility Study of Compensation for Blindness with PRIMA System for Dry AMD

This clinical trial is a feasibility study being conducted in France and the United States. The study in France has recruited and implanted the device in 5 patients.  The first implant in France was performed January 25, 2018.  

On August 30, 2018 Pixium Vision Chief Executive officer Khalid Ishaque, stated: "The successful consecutive activations of PRIMA in all five implanted study patients, combined with the preliminary clinical results and progress with the first implanted patients, are very encouraging for the clinical development of PRIMA. We look forward to reporting on the continued progress of the feasibility study, including the interim six-months combined follow-up data for the five patients, and the next phases of clinical development of PRIMA in Europe and in the United States."

Pixium Vision Update
January 8, 2019

Pixium Vision's press release of January 8, 2019 reports their interim 6 month study data of patients with advanced dry AMD:

"1.  Implant is well tolerated while preserving residual peripheral vision acuity

 2.  All subjects report light perception in their central visual field

 3.  Majority of patients identifying complex patterns, letters or letter sequences

 4.  Interim positive data enables to prepare the European multi Centre pivotal study"

Here is a short video on how the Photovoltaic Retinal Implant system works:

You can go to www.ClinicalTrials.gov website to learn more about the study here:

Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular Degeneration

PRIMA US-Feasibility Study in Atrophic Dry AMD

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