Silicon floaters in my eye after avastin injection for wet amd

by Joan Mc
(Sioux Falls, SD, USA)

I have had dry amd for probably 10 years or more. I am 76. Last year, my left eye developed wet AMD. I have been treated with injections of Avastin and am on a 9 week schedule.


After my last injection, I developed several large floaters that stayed in the lower right quadrant of my eye. I did go back to my retinal specialist in a few days and he diagnosed these floaters as silicon drops from the coating on the needle used for injection.

I'm wondering if anyone else has had this experience? If so, did the silicon floaters go away, dissolve, or are they a permanent thing? They are irritating, and I keep thinking I've spilled something on myself....hard to tell illusion from reality!

Would appreciate any info, any idea of how often this occurs.

Thanks!

Joan Mc

Comments for Silicon floaters in my eye after avastin injection for wet amd

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Aug 23, 2018
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Black Floaters
by: Anonymous

Hello, I received a shot of Avastin back in March of 2018 and had a large bubble of black. I spoke with the doctor and he said that it should go away in a day or two.

It did change but seemed to have broken up into many little black spots. Went back to the doc and he said that he had broken through the eye wall (not sure what that really means yet) but that the black floaters would go away in a few weeks.

Went back in May 2018 and floaters are still there. Then he said that it can take up to a year for them to go away. Last appointment in Aug of 2018 and still have floaters. Very distracting.

Jul 19, 2018
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Avastin Floaters
by: Susan D

I was diagnosed with wet AMD in my right eye and dry AMD in my left eye in 2016. Avastin shots were started and during my 2nd shot I was left with a whole field of small black floaters. I told my retinal doctor and he immediately reported it.

I have been getting shots in my right eye every 3 months and then he accesses the eye for bleeding then makes the decision as to whether I get 3 more months of shots or get to abstain for 3 months. At each assessment appointment both eyes are checked. One week after an assessment in 2018 I woke up one morning and was seeing distortion in my left eye. That eye went from dry to wet, I believe, overnight. I went right in that day to the retinal doctor and he confirmed the wet MD and gave me a shot right away.

I believe that saved that eye from further damage that day. By the way, the doctor had told me about the new needles that would not cause any floaters and switched to using them as soon as they were released. My floaters have never gone away but I don't notice them in the house very much but when outside they show me they are still there. I do think in some circumstances my brain ignores them and then I don't see them. I am 69 now (2018) and both my parents had macular degeneration; I believe MD is hereditary.

Jul 12, 2018
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Ocular Histoplasmosis
by: Anonymous

I have been getting injections for 3+ years now for ocular histoplasmosis. I have had 28 injections over that period into my right eye.

I just went yesterday for one, and I have these black spots every where. They are big at first and then get smaller but it seems as if they are ALWAYS there. They never really seem to go away. It's like looking through a dirty windshield at all times and i am constantly swatting at bugs that are not there. It's torture.

Jun 18, 2018
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SILICONE FLOATERS SINCE 3-21-2018
by: Anonymous

I was diagnosed with wet macular degeneration (right eye) in October 2017 and had my first injection of Eyelea. Everything was clearing up so the doctor decided to change the medicine to Avastin. I asked him why he was changing the drug, and he said it was because it was cheaper.

So my first injection of Avastin was March 21, 2018, and as I was walking to the waiting room, I saw a pea sized blob of black and 50+ black circles w/white centers(all different sizes large/larger, small/smaller, and tiny). The doctor changed the medicine back to Eyelea, but I still have about 20 of these silicone floaters as of today (6-18-2018). I really see the floaters in the light and see them less in a room with less light. I'm always swatting at a perceived bug by my right eye, but none there.

Jun 08, 2018
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Avastin: Flashes and Floaters
by: JMM

Diagnosed with AMD April 2018. First 2 shots were OK but had a problem with eye pain, tearing and eye sensitivity. Goes away after 5 hours.

After 3rd shot this week experiencing subtle flashes and many floaters. Returned to doc to ensure retina is OK. All checks out and will return in 2 weeks to see if I"m having the same symptoms.

Jun 06, 2018
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Silicone Eye Floaters
by: Anonymous

After getting eye floaters from an Avastin injection with a silicone coated needle, I complained enough that my ophthalmologist switched me to Eyelea which doesn't use a coated needle. I haven't had any further problem with floaters, though they haven't gone away.

Jun 06, 2018
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Floaters after avastin injections
by: Anonymous

I was diagnosed with wet AMD in December, 2017 and recieved my first eye injection then. It was surprisingly painless and I did not experience any floaters at that time.

Since that time, I received three eye injections and each one resulted with what looked like two BBs injected into my eye.

This happened immediately with each injection. I asked the nurse about this and she said they were air bubbles and would go away. The spots, floaters, are like drops of oil suspended in water.

Jun 01, 2018
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Ask for Silicone-Free Syringes
by: Anonymous

Why not use silicone-free syringes. They are now available from https://www.westpharma.com/blog/2017/September/when-silicone-oil-is-not-an-option and other sources. Is the ophthalmology industry invested in a product with known undesired consequences? A patient has the right to request a fundamentally safer syringe!

May 23, 2018
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Floaters as well
by: Anonymous

I just had my first injection and have a large circular floater! Looking forward to morning hoping it will disappear.

May 05, 2018
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Silicone floaters after Avastin injections
by: Anonymous

I commented back in February about the silicone floaters after Avastin injections. At that time I had them for three days. They lasted 4 weeks at that time and finally went away but I still get a few after the shots of Avastin.

May 05, 2018
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Update
by: Anonymous

I finally have had some replies to my inquiries. Both FDA and Genentech have been in contact.

The hang up right now is getting information in regard to silicone oil specifics( batch # etc) used for the syringe. FDA needs that to search their database for other reports related to that batch.

Will have to persevere. My suspicion is that the compounding lab has that information. Are they dragging their feet?

My doctor is very good about keeping me informed on the research he is involved in. So far, the Lucentis injections have been keeping both eyes stable.

I am waiting for communication from Genentech to authorize the Retina Clinic to release my records.

Progress. Slow. Hope I live long enough to see the results.

May 05, 2018
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Floaters
by: Joanamc2@aol.com

I complained to my retinal specialist about the floaters and he switched me to Eyelea which does not come with a prepackaged silicone coated needle.

Apr 21, 2018
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Still gathering information
by: Anonymous

Has anyone received injections with the special needles made for eye injections... and where?
I can’t believe that with the large number of people all across the country being treated for AMD there hasn’t been a push to abandon the silicone oil coated syringes.
Europe has been using them for years.
I live in Oregon. Does anyone know of a Clinic who uses the newer needles?
Anyone in Washington getting treated at a Retina clinic using the newer needles?
That information is near impossible to find out!

Apr 07, 2018
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appreciate the info mike
by: Anonymous

thanks for letting us know

Apr 05, 2018
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Black floaters after Avastin injections
by: Anonymous

I have received Avastin in both eyes for over two years and recently developed the black floaters. I always have them for a short while but then they disappear this time I had them for four weeks and they finally left. That are extremely irritating. Hope yours go away.

Mar 20, 2018
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Update on silicone Floaters
by: Mike S.

Since my last post, Jan 25, I received a Wet AMD shot of Avastin with a new, smaller needle that does not have the silicone coating. It is a .32 gauge needle and actually was much less painful than the previous needles. Ask your doctor.

Feb 26, 2018
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Eye Floaters
by: Ramarao

I had cataracts in both eyes and consulted an ophthalmologist about this. He suggested that I go for surgery but said that if I can manage, if I am happy with the quality of my life, I may wait.

I discussed the issues and risks with my son and we felt that I can get the surgery for one eye. Since both the eyes are affected, I chose the left eye. The doctor confirmed that there was no AMD in either eye,in an answer to my specific question.

The surgery was done and the bandage was removed the same night. The next morning, I noticed a dark patch in central vision of left eye, where the surgery was done. After examination,the doctor said that there was some swelling and it will go away in a few days. The dark patch did not go away after 7 days. He changed the eye drops,said the swelling had decreased and asked me to come for a check up after a week.

The dark patch remained put and after one week the doctor said there was some other problem and referred me to a Retina specialist. That doctor examined and pronounced that I have wet AMD, it must have been there for awhile, even before the cataract surgery.

Well,,this took me by surprise since I never experienced its presence nor the first surgeon found it. So I have started on Avastin injections,I had 2 in the last 6 months, each injection being preceded by eye examination.

I had consulted 3 doctor’s in the meanwhile but none could say how I could have developed AMD overnight. They all opine that the first surgeon must have missed out. That could not be since I was looking at the Amsler grid quite often at home

.There you are and now I am looking for aids..I am also in a dilemma about cataract surgery for my right eye. Any suggestions!
After 8 months, and after the rd injection,I find a floater at the left lower corner of my left eye and a small floater coming up.
Thanks.C.RamaRao.


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Feb 16, 2018
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Floaters after Avastin injections
by: Anonymous

I have been having Avastin injections for almost three years in both eyes and always have some dark floaters immediately after the injections. They usually are gone by the next day but this time it has been three days and I still have one floating around. I will wait a few more days and if no better will contact the retina a specialist.

Jan 25, 2018
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Silicon Floaters in My Eye
by: Mike S.

I have been getting the Avastin injection for Wet AMD in my left eye for four years. I recently noticed the black floaters increasing in size and number.

My Doctors says they have seen an "uptick" in this over the past year. They seem to grow by coagulating over time and do not go away. Mine resemble a crescent shaped constellation in the sky. Very frustrating. The doctor said there was a surgical procedure they could perform to get rid of them, but they will come back if I continue to receive the Avastin injections.

Nov 10, 2017
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Silicone bubbles in eye from Avastin
by: Joan Mc

Thanks for responses. I am now on Eye after the silicone bubbles from Avastin needles. Hadn't thought of contacting the FDA but may do that. I googled the topic several months ago and saw an attorney group in Cleveland was interested in cases like this. Don't now remember the name but think I have it at home. I'm on a trip now. Bubbles are still there. Yes, very annoying!

Nov 10, 2017
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We need to track this
by: Anonymous

If people report these apparently permanent floaters, we may be able to track the syringes back to the compounding lab.
We owe it to others to prevent this from happening.

Oct 23, 2017
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To Joan MC
by: Anonymous

I hope your floaters will still go away, or at least break up and go to the bottom of the eye. Mine is still there, bopping around with every eye movement. It is beyond annoying, and I dread having to live with this the rest of my life.

But I will continue the injections, now with Lucentis. They keep me from losing my eyesight.

I hope everybody with those seemingly permanent floaters contacts the FDA. I sincerely feel that compounding Avastin increases the chance of the silicone oil separating from the needle and getting into the meds.

Noodle

Oct 16, 2017
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Permanent Large Disk after Avastin injection
by: Anonymous

I hadn't checked this site for awhile, as my previous posting didn't get any replies.
It has been 9 months since I experienced tha large disk shaped floater. It is still there. Black outline, almost neon bright white
on the inside.
I have done enough research to conclude that it is the fault of the compounding lab... The silicone oil separated from the needle. Either due to negligence or faulty transport ( shock, freezing/ thawing).
Reported it to FDA. Received a questionnaire from Genentech ( manufacturer).
Silence since then.
I hope others will come forward.
This was avoidable. It is definitely effecting my quality of life, causes balance problems, vision problems, beyond annoying.

Oct 11, 2017
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Floaters after Avastin Injections
by: Anonymous

This has become a problem for me since July and August injections. The floaters were like a blizzard after the August injection. They are still present, but have consolidated into smaller numbers, but larger size.

Jul 11, 2017
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Floaters
by: Anonymous

I have had something similar after injections. I get what I call bubbles of the medicine. They only last a day or two. Hopefully yours will dissolve soon.

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