Wet Macular Degeneration Clinical Trials
Macular Degeneration Research
There are many more wet macular degeneration clinical trials than there are for dry age related macular degeneration.
You will find the most complete international listing at the National Institute of Health website www.clinicaltrials.gov There are usually less studies recruiting for dry macular degeneration than there are for the wet form. Currently (June 2010) there are 39 clinical trials for wet AMD, but only 19 of them are in the United States. Here are some samples of macular degeneration clinical trials that are recruiting new participants.
Wet AMD Clinical TrialsLucentis Injections Combined with Photodynamic TherapyThese clinical trials are looking at the effectiveness of combining two FDA approved therapies for AMD - Lucentis injections and Photodynamic therapy. There are several studies that are still recruiting participants. If this interests you click on the link below and then look for studies that say "Recruiting."Look at the eligibility criteria to see if you might be eligible. If you think you are, then scroll down to Contacts and look for the closest study site to where you live and contact the study coordinator. Lucentis and Visudyne (Photodynamic Therapy) Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT)The United Kingdom is offering this Phase IV study at 15 different locations for patients with subfoveal choroidal neovascularisation associated with wet age-related macular degeneration. Here is a description:"This study tests a new surgical device that delivers a focal dose of radiation (epimacular brachytherapy) to the macula, to try and reduce or eliminate the need for ongoing, regular eye injections. The trial compares epimacular brachytherapy to ongoing standard treatment with ranibizumab." Those that are eligible for this study must have received anti-VEGF treatment. To find out if you're elibile for this wet AMD study click here: Radiation for Wet AMD Lucentis and Radiation TherapyIf you live in the California area and have wet AMD, there is a wet macular degeneration clinical trial that is looking at the synergistic effect of combining Lucentis injections with radiation. If you want to know more about this trial go to: Lucentis and RadiationSupplemental Adjuvants for Intracellular Nutrition and Treatment"The potential for protecting the DNA and promoting repair by using nutritional supplements will be tested by augmenting standard treatments for DME and NAMD with such supplements.The patients will be randomized to treatment group and placebo group and followed up for a year in a double masked fashion." Supplemental Adjuvants for Intracellular Nutrition and Treatment
TheraSight Ocular Brachytherapy SystemAccording to Dr. G. Baker Hubbard, M.D., Emory Eye Center retinal specialist, "This system (ThereSight System) has potential as a one-time treatment for select patients with wet AMD, and may have benefit for patients with large sub-foveal lesions, a difficult subset of AMD patients with no currently approved treatment options."To read more about the Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy System
click here:
TheraSight
Study for Subfoveal Choroidal Neovascularization - NEW!A Study of the NeoVista Ophthalmic System for the Treatment of Subfoveal CNV Associated With Wet AMD in Patients That Require Persistent Anti-VEGF Therapy (MERITAGE)Here is a description of this trial: "The objective of the MERITAGE Trial is to evaluate the safety and efficacy of focal delivery of radiation for the treatment of subfoveal choroidal neovascularization (CNV) associated with wet age-related macular degeneration (AMD) in patients that require persistent injections of Anti-VEGF therapy to maintain an adequate response to treatment." This study is taking place in Phoenix, Arizona. For more information click here:
Subfoveal CNV Clinical Trial
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