Dry Macular Degeneration Clinical Trials

Dry macular degeneration clinical trials are becoming more available as new treatments and earlier intervention is being researched.

Dry Macular Degeneration Treatment

However, dry macular degeneration clinical trials are not as prevalent as they are for wet age related macular degeneration.

Dry Macular Degeneration Studies

As of December 2011, there are 32 studies listed on the U.S. National Institutes of Health website that are currently recruiting new participants.

There are several things you want to consider when you consider a clinical trial.



Where is the Study Being Conducted

The clinical trials that are listed at www.clinicaltrials.gov are not just in the United States, but rather it is an international database. So it is important to look at the location of the study. Right now out of the 8 studies available, most of them are outside the United States. They are in in Israel, Canada, Switzerland, Austria, Sweden and Germany.

What Treatment is Being Investigated

Of the studies that are in the United States, one of them is testing the safety of transplanting human fetal neural retinal tissue and retinal pigment epithelium into the eyes of human patients with age-related macular degeneration.

The second study listed is "Weekly Vaccination With Copaxone as a Potential Therapy for Dry Age-Related Macular Degeneration."

Copaxone is an immunomodulatory substance which has shown to be an effective drug in arresting the progression as well as the conversion of dry AMD to wet AMD.

What Phase is the Study In

There are four stages. Stage I being the first stage that tests for safety. The last is Stage IV. Click her for more detailed information: Clinical Trial Phases

To perform a search of current clinical trials click on the link below and in the search field type in, "dry macular degeneration" without the quotes. www.ClinicalTrials.gov

Here is a sampling of some current dry macular degeneration clinical trials:

1. Early Dry AMD Clinical Trial

Effect of Lutein-Enriched-Egg Beverage on Early AMD

Maastricht University Medical Center did a pilot study in 2007 that showed a substantial increase in plasma lutein levels and a increase in macular pigment optical density after only 3 months of daily consumption of a lutein-enriched egg-beverage.

They now want to study the effect these changes have on subjects with early (undiagnosed) stages of macular degeneration. With this trial they hope to show that with daily consumption of this enriched beverage, they can slow the progression of AMD.

To learn more about the criteria and purpose of this study click here: Lutein Enriched Egg Beverage Study for Early AMD

2. ACU-4429 in Subjects With Geographic Atrophy

A Phase II clinical trial will be looking at the effectiveness of ACU-4429. This drug is meant to block the enzyme isomerase to help slow down the progression of dry AMD.

This clinical trial is taking place in Austin and Dallas, Texas.

Click here to find out more about this study and to get contact information:


ACU-4429 in Subjects With Geographic Atrophy

3. Intravitreal Injections of FCFD4514S in Patients With Geographic Atrophy

This is a Phase I clinical trial which means it is primarily look at the safety and tolerability of the study drug which is an intravitreal injection of FCFD4514S - which means it is injected into the eye.

You must be between the ages of 50 - to 85 years old and be diagnosed with geographic atrophy.

There are 5 study locations - all in the United States. Click here to get the list of locations and contact information.

Intravitreal Injections of FCFD4514S in Patients With Geographic Atrophy

4. Safety and Tolerability of Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Advance Dry AMD

Jules Stein Eye Institute in Los Angeles, California is participating in a Phase I/II study using stem cells in patients with advanced dry macular degeneration.

Participants must be 55 or older and not have any signs of wet macular degeneration. Because it is a Phase I study the number of participants is

The purpose of the study is "to evaluate the effect of subretinal injection of human embryonic stem cell derived retinal pigment epithelium cells in patients with dry AMD."

Find out more about this macular degeneration research here: Macular Degeneration and Stem Cells

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