Back to Back Issues Page
What Are Anti-VEGF Eye Injections and How Do They Help with Vision Loss
June 13, 2019

What Are Anti-VEGF Eye Injections and How Do They Help with Vision Loss

In 2004 a new class of drugs used to treat macular degeneration became FDA approved. This class of drugs is called anti-VEGF. VEGF stands for vascular endothelial growth factor and anti of course means to halt or stop.

The mechanism of these drugs is to halt, stop or delay the progression of fragile and abnormal tiny blood vessels that develop under the macula. Instead of being useful blood vessels that bring oxygen and nourishment to the macula or help to remove waste products, these blood vessels are useless and in fact are harmful. The walls of the blood vessels are not normal - but rather very fragile. As a result blood and fluid leak from them.

Wet Macular Degeneration Symptoms

The build up of fluid raises the macula which needs to lie flat. When the macula is raised, a person experiences a distortion in their vision, such as straight lines appearing wavy or bent.

The fluid also damages the surrounding photoreceptor cells. With damaged photoreceptor cells, there is diminished vision. One's vision appears blurry rather than sharp, colors are not as distinct, and there is a need for more light.

Anti-VEGF Therapy

Anti-VEGF therapy interferes with the growth of these new blood vessels and has been shown in clinical trials to help maintain and stabilize one's vision and in some patients help to improve their vision.

Learn more about how these medications work, what improvements one might expect, and if there are possible side effects:

Wet Macular Degeneration anti-VEGF Therapy

Leslie Degner, RN, BSN

Better Health for Better Vision

Back to Back Issues Page