|Vitamin B complex benefits the eyes and especially the macula according to an observational study reported on in the Archives of Internal Medicine in February of 2009.|
An observational study of 5442 female health care professionals 40 years or older with preexisting cardiovascular disease or 3 or more cardiovascular disease risk factors was conducted by Brigham and Women's Hospital, Harvard Medical School.
"Examine the incidence of age related macular degeneration in a trial of combined folic acid, pyridoxine hydrochloride (vitamin B6), and cyanocobalamin (vitamin B 12) therapy."
Participants were randomly assigned to receive a combination of:
1. Folic Acid (2.5 mg/d),
2. Vitamin B6 (50 mg/d) and
3. Vitamin B12 (1 mg/d)
After an average of 7.3 years of treatment and follow-up, there were
55 cases of AMD in the combination treatment group and
82 cases of AMD in the placebo group
(relative risk, 0.66; 95% confidence interval, 0.47-0.93 [P = .02]).
For visually significant AMD, there were
26 cases of AMD in the combination treatment group and
44 cases of AMD in the placebo group
(relative risk, 0.59; 95% confidence interval, 0.36-0.95 [P = .03]
The conclusions of this study were:
"These randomized trial data from a large cohort of women at high risk of cardiovascular disease indicate that daily supplementation with folic acid, vitamin B6, and vitamin B12 may reduce the risk of AMD."
Vitamin B complex benefits for macular degeneration seem to involve homocysteine levels.
As reported in Science News, February 234, 2009
"Increased homocysteine levels have been shown in many studies involving age-related macular degeneration," says ophthalmologist Sibel Kadayifcilar of Hacettepe University Medical School in Ankara, Turkey.
"However, we still don't know whether homocysteine is causative or only a marker." Meanwhile, other research shows that a vitamin B-12 deficiency is a risk factor for macular degeneration."The vitamin B complex my husband and I take regularly is one made by Twin Labs called Twinlab Stress B-Complex Capsules with Vitamin C.