Silicon floaters in my eye after avastin injection for wet amd

by Joan Mc
(Sioux Falls, SD, USA)

I have had dry amd for probably 10 years or more. I am 76. Last year, my left eye developed wet AMD. I have been treated with injections of Avastin and am on a 9 week schedule.

After my last injection, I developed several large floaters that stayed in the lower right quadrant of my eye. I did go back to my retinal specialist in a few days and he diagnosed these floaters as silicon drops from the coating on the needle used for injection.

I'm wondering if anyone else has had this experience? If so, did the silicon floaters go away, dissolve, or are they a permanent thing? They are irritating, and I keep thinking I've spilled something on myself....hard to tell illusion from reality!

Would appreciate any info, any idea of how often this occurs.


Joan Mc

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Nov 10, 2017
We need to track this
by: Anonymous

If people report these apparently permanent floaters, we may be able to track the syringes back to the compounding lab.
We owe it to others to prevent this from happening.

Oct 23, 2017
To Joan MC
by: Anonymous

I hope your floaters will still go away, or at least break up and go to the bottom of the eye. Mine is still there, bopping around with every eye movement. It is beyond annoying, and I dread having to live with this the rest of my life.

But I will continue the injections, now with Lucentis. They keep me from losing my eyesight.

I hope everybody with those seemingly permanent floaters contacts the FDA. I sincerely feel that compounding Avastin increases the chance of the silicone oil separating from the needle and getting into the meds.


Oct 16, 2017
Permanent Large Disk after Avastin injection
by: Anonymous

I hadn't checked this site for awhile, as my previous posting didn't get any replies.
It has been 9 months since I experienced tha large disk shaped floater. It is still there. Black outline, almost neon bright white
on the inside.
I have done enough research to conclude that it is the fault of the compounding lab... The silicone oil separated from the needle. Either due to negligence or faulty transport ( shock, freezing/ thawing).
Reported it to FDA. Received a questionnaire from Genentech ( manufacturer).
Silence since then.
I hope others will come forward.
This was avoidable. It is definitely effecting my quality of life, causes balance problems, vision problems, beyond annoying.

Oct 11, 2017
Floaters after Avastin Injections
by: Anonymous

This has become a problem for me since July and August injections. The floaters were like a blizzard after the August injection. They are still present, but have consolidated into smaller numbers, but larger size.

Jul 11, 2017
by: Anonymous

I have had something similar after injections. I get what I call bubbles of the medicine. They only last a day or two. Hopefully yours will dissolve soon.

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