Is Macular Degeneration Hereditary?
Macular Degeneration TestIt becomes all the more important to pay attention to the other risk factors and
causes of AMD
if you have this family history, as in my husband's case. His father was diagnosed with macular degeneration 15 years ago and all of his father's siblings had the same macular degenerative disease. This means my husband has a 50 % chance of developing this central loss of vision. Therefore, we are all the more diligent in making sure he wears his yellow tinted sunglasses, eats salmon, includes spinach in his diet and takes antioxidant supplements. Several of the genes associated with macular degeneration have been identified. As a result there is now a macular degeneration test to see if a patient has any of the genes associated with age related macular degeneration. Find out how a person is tested for these genes as well as who would benefits from genetic testing. Macular Degeneration Test for Genes Macular Degeneration StatisticsAccording to Dr. James C. Folk, author of Protect Your Sight: How to Save Your Vision in the Epidemic of Age-Related Macular Degeneration , "Studies have shown that the risk of AMD is much higher for people whose family members have the disease than for people who have no family history of AMD."Consider these numbers: √ Approximately one fourth of all late-stage macular degeneration appears to be related to genetics 
√ The lifetime risk of developing late-stage macular degeneration is 50% for people who have a relative with macular degeneration vs 12% for people who's relatives do not have macular degeneration (4x the risk). √ If you have first-degree relatives with late-stage macular degeneration you will develop macular degeneration at an increased rate at a younger age. Arch Ophthalmol.1998;116:1646-51) If you find these macular degeneration statistics a bit alarming for you or for your children, consider taking preventative measures now to reduce your chances (and your children's) of developing macular degeneration. Click here to read more about macular degeneration prevention. Macular Degeneration Prevention Genes and Macular DegenerationCurrently there are several clinical trials looking at identifying the genes that may be responsible for the development of AMD. As of September 2010 they are:1. Genetic Factors in Age-Related Macular Degeneration "This study will examine whether certain polymorphisms (small gene variances) predispose people to develop age-related macular degeneration (AMD). The study will examine and compare the frequency of polymorphisms in patients with AMD to that of individuals without AMD. This information will help identify genetic risk factors for the AMD and may lead to the development of more effective treatments." Study Location: National Institutes of Health Clinical Center, Bethesda, Maryland, United States 2. Genetics and Markers of Degenerative and Inflammatory Eye Diseases "This study will identify genes that are associated with inflammation or degeneration of the retina (membrane lining the back of the eye that relays vision signals to the brain). It is thought that many retinal conditions are due to an altered immune system and are based on how the person's genes function and communicate." Location: National Institutes of Health Clinical Center, Bethesda, Maryland, United States 3. Repository for Inherited Eye Diseases "This study will collect blood and DNA samples from patients with inherited eye diseases to be used in research to identify genetic factors responsible for these conditions. In recent years, nearly 500 genes that contribute to inherited eye diseases have been identified. Disease-causing mutations are associated with many eye diseases, including glaucoma, cataracts, strabismus, corneal dystrophies and a number of forms of retinal degenerations." Location: 24 Study Locations To go to the National Institutes of Health website for a listing of these clinical trials click here: Clinical Trial Listing regarding Macular Degeneration and Genes Cause of Macular DegenerationFamily history is not the only factor for the development of AMD. The other big one is age.Dr. James C. Folk the author of Protect Your Sight: How to Save Your Vision in the Epidemic of Age-Related Macular Degeneration Although one cannot choose their parents or keep from aging, there are lifestyle choices we can make that can help prevent or delay this macular eye disease from developing in our own eyes. Find out about other
causes of macular degeneration.
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writes about the concern of whether macular degeneration is hereditary, "AMD is most strongly associated with age and a family history of the disease."